Lasers for Biophotonics & Microscopy
TOPTICA offers laser solutions for a multitude of biophotonics applications
- Confocal Microscopy
- Raman Spectroscopy and Microscopy
- Flow Cytometry
- Fluorescence Detection and Imaging
- SHG Microscopy
- High Content Screening (HCS)
- FLIM, FRET, FRAP etc.
- CARS Microscopy
- Multiphoton Microscopy
- Wide Field Imaging Techniques (e.g. TIRF)
- Super Resolution Imaging including STED, PALM, STORM
- Medical Imaging (e.g. Fluorescin Angiography)
- Microplate Readers
- High Throughput Screening (HTS)
- DNA Gene Sequencing
A considerable amount of our knowledge about the functions of proteins, cells or complete organs has been gained with optical techniques. Light enters a cell, probes it and provides valuable information. Amongst others, modern optical techniques unite high spatial resolution, non-destructive sampling, deep penetration and even three-dimensional imaging. They can provide in-situ or in-vivo examinations and allow for real-time observation.
Lasers play an invaluable part in optical instrumentation ranging from microscopy to flow cytometry, medical and pharmaceutical instruments. The steadily growing number of optical technologies in Life Science and Medical applications goes hand in hand with the increasing demand for modern photonic sources - each one optimized to perfectly serve its specific task.
TOPTICA Photonics is proud to be one of the world leading suppliers for demanding Biophotonical applications. Our thought through portfolio reaches from high quality UV and VIS laser sources with direct modulation capabilities to widely tunable reliable fiber-based lasers and ultrafast pulsed sources for time-resolution sensitive applications. TOPTICA represents itself as a highly knowledgeable, flexible and reliable one-stop partner for our customers in the field of Biophotonics.
TOPTICA supports PIX4life project to miniaturize lasers for life sciences
Miniaturized PIC multi-color laser engines for the life sciences
In February 2016 the European commission approved funding for the new project PIX4life as part of the EU’s “Photonics21” program . TOPTICA is proud to support this unique program which pledges [...] pledges € 8.5 million to a consortium of several partners from academia and industry.
The European PIX4life pilot line aims to offer an open-access manufacturing platform for photonic integrated circuits, specifically targeting life-science applications at visible wavelength ranges (400-850 nm). Chip fabrication will be done either through dedicated wafer runs, or most often by multi-project wafer (MPW) runs, where many users will be able to share wafer space, and thus the fabrication cost. PIX4life will also offer all kinds of additional services like photonic integration consultancy, circuit design, chip testing and packaging.
The first early-access MPW run by LioniX is scheduled for this summer over their TriPleX platform, and the next run by IMEC will be scheduled for this winter over their BioPIX platform.
Time-resolved microscopy and spectroscopy using asynchronously
synchronized fiber lasers (2018)
Application Note 2018
Synchronized modular laser systems support time-resolved measurements, as well as complex pump-probe methods like ASOPS. The presented laser system is used to measure Kerr-rotations by inducing a precession motion of the spin magnetization in ferromagnetic materials, which in turn leads to emission of microwave radiation that rotates the polarization of temporally delayed probe pulses. This way, the temporal evolution of the spin precession motion is detected.